“Generate Surface Tangents” needs texture coordinates to generate the tangent because it needs a direction for the tangent. There is theoratically an infinity of tangents at a point so it needs some constraints to generate something, as you’d need if you want to compute it yourself.
So either you have some implicit constraint that you know and that you can implement in a Python calculator or something, either the output of your simulation lacks data.
I think this is kind of similar to Calculation of surface tangents error