Hi, ParaView Glance can certainly interact with a server of your choosing. In fact, that’s usually preferable to running AI models in the browser depending on how fast the model can run. So yes, Glance can show the ROI results of your algorithm as a paint overlay on an image. Note that the Glance codebase has to be modified to pull results from a server or run a custom algorithm in the browser, as there’s no easy way to generally support this functionality out-of-the-box.
You mentioned DICOM, so I just wanted to also mention another tool being developed that could be of interest to you. ParaView Medical aims to be similar to ParaView Glance, but for medical images (e.g. DICOM).
If you are interested in getting more help for customizing Glance to fit your needs, feel free to direct message me and we can discuss your requirements further. (FYI I’m a core dev for both ParaView Glance and ParaView Medical.)